Miscarriage Testing

This was posted with permission from my friend ozgal who did a lot of info gathering. It's a list of all the different types of testing that you can get done. My ob/gyn today suggested that I just get the IgG and IgM tests done -- as they more common blood clotting disorders. I'll get the results in a few days time.

Here's a list of suggested post-m/c tests (with resources below):

• Toxoplasmosis


• Antinuclear Antibody Titre (ANA)


• Anti dsDNA Antibody


• Anti ENA screen (ELISA)


• APA – Antiphospholipid Antibodies (Anticardiolipin antibodies)


• Lupus Anticoagulant


• Thrombotic Assays (for clotting factors):

-- Antithrombin III Activity
-- Protein C Assay (functional)
-- Protein S Assay (free)
-- Plasminogen Assay
-- Activated Protein C Resistance (Factor V Leiden)

• Serum Immunoglobulins (IgG, IgA, IgM)


• Fertility hormones: Progesterone, HcG, Prolactin


• RIP (Reproductive Immunophenotype – natural killer (NK) cell)


• NKA (NK cell assay)


• Antihistone Antibody


• Coagulation Assay


• DQ alpha HLA antigen (male and female)


• LAD (Lymphocyte Antibody Detection) (male and female)


• TNF alpha (Tumor Necrosis Factor)


• Antibodies to neurotransmitters


• ETA (embryotoxicity assay)


• Ratio of TH1 to TH2


• Genetic/karyotyping of male/female blood


• DNA Integrity Assay (this requires sperm analysis)

Sources:
Dr. Jonathan Scher and Carol Dix, Preventing Miscarriage, the Good News. New York: Harper Collins, 2005.
Jon Cohen, Coming to Term: Uncovering the Truth About Miscarriage. New York: Houghton Mifflin, 2005.
http://www.repro-med.net/info/cat1-5.php
http://www.haveababy.com/rpl/basics.asp
http://www.illinoisivf.com/recurrent-pregnancy-loss/post-implantation.html
http://www.inciid.org/article.php?cat=immunology&id=374&pagenumber=1
http://www.asklenore.info/miscarriage/immune_testing.html
http://www.rialab.com/miscarriages_prevented.php
http://sharedjourney.com/loss.html
http://www.infertilitytutorials.com/miscarriage_members/hormonal.cfm
http://news.bbc.co.uk/2/hi/health/4002539.stm
http://www.gentlebirth.org/archives/miscrg.html#Prevention
http://www.sefertility.com/patinfo_progesterone.html

Please send her some prayers as thank you for sharing. She'll need them as she works on TTC post loss.