Tuesday, June 06, 2006

Miscarriage Testing

This was posted with permission from my friend ozgal who did a lot of info gathering. It's a list of all the different types of testing that you can get done. My ob/gyn today suggested that I just get the IgG and IgM tests done -- as they more common blood clotting disorders. I'll get the results in a few days time.

Here's a list of suggested post-m/c tests (with resources below):


  • Toxoplasmosis

  • Antinuclear Antibody Titre (ANA)

  • Anti dsDNA Antibody

  • Anti ENA screen (ELISA)

  • APA – Antiphospholipid Antibodies (Anticardiolipin antibodies)

  • Lupus Anticoagulant

  • Thrombotic Assays (for clotting factors):

  • -- Antithrombin III Activity
    -- Protein C Assay (functional)
    -- Protein S Assay (free)
    -- Plasminogen Assay
    -- Activated Protein C Resistance (Factor V Leiden)
  • Serum Immunoglobulins (IgG, IgA, IgM)

  • Fertility hormones: Progesterone, HcG, Prolactin

  • RIP (Reproductive Immunophenotype – natural killer (NK) cell)

  • NKA (NK cell assay)

  • Antihistone Antibody

  • Coagulation Assay

  • DQ alpha HLA antigen (male and female)

  • LAD (Lymphocyte Antibody Detection) (male and female)

  • TNF alpha (Tumor Necrosis Factor)

  • Antibodies to neurotransmitters

  • ETA (embryotoxicity assay)

  • Ratio of TH1 to TH2

  • Genetic/karyotyping of male/female blood

  • DNA Integrity Assay (this requires sperm analysis)



Sources:
Dr. Jonathan Scher and Carol Dix, Preventing Miscarriage, the Good News. New York: Harper Collins, 2005.
Jon Cohen, Coming to Term: Uncovering the Truth About Miscarriage. New York: Houghton Mifflin, 2005.
http://www.repro-med.net/info/cat1-5.php
http://www.haveababy.com/rpl/basics.asp
http://www.illinoisivf.com/recurrent-pregnancy-loss/post-implantation.html
http://www.inciid.org/article.php?cat=immunology&id=374&pagenumber=1
http://www.asklenore.info/miscarriage/immune_testing.html
http://www.rialab.com/miscarriages_prevented.php
http://sharedjourney.com/loss.html
http://www.infertilitytutorials.com/miscarriage_members/hormonal.cfm
http://news.bbc.co.uk/2/hi/health/4002539.stm
http://www.gentlebirth.org/archives/miscrg.html#Prevention
http://www.sefertility.com/patinfo_progesterone.html

Please send her some prayers as thank you for sharing. She'll need them as she works on TTC post loss.

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