Tuesday, January 10, 2006

Bad Estrogen

Sounds dramatic doesn't it but there really is estrogen known to be the bad kind, the kind that can lead to cancer. Since I'm not doing acu treatment or chinese herbs right now and its just up to me to try to fix me I decided to do some more research into PMS and estrogen. It's that time of the month (mid-luteal phase) and my breasts are so uncomfortable. The only time I've had real relief for a while was after both pregnancies, I guess due to the pregnancy types of estrogen being dominant then.

So here are some of the links I came across that interested me:

Predictors of the plasma ratio of 2-hydroxyestrone to 16-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups

The relationship between physical activity and 2-hydroxyestrone, 16alpha-hydroxyestrone, and the 2/16 ratio in premenopausal women

DIM (Di-Indoly Methane)For Natural Protection from Estrogen's Effects

What I picked out that might relate to me are:

...that since dietary therapy alone hasn't helped, and my mother had PMS as well that there might be a heriditary factor.

...that exercise really might help my body to metabolize the bad estrogen more

...that taking DIM for a while might not be such a bad idea, at least to see if I can detect any changes.


Claire said...

Hi Ann,

Great links! I hope you find some more. I have been really curious about this estrogen metabolism stuff. I have a really high 16-alphahydroxyestrone level. I'd like to get that lower, but don't know if it's possible. I guess the other way to do it is to get the 2-hydroxyestone higher through exercise.

Thanks! Claire

agness said...

How do you know what your 16-level is? Who tested it and why?

I'm sure I could talk one of my docs into testing it for me but it doesn't seem to be a standard thing.